Hu Rong

Publisher:基础医学Release time:2017-12-26Times of browsing:219

Rong HuPh.D. Professor

 Department of Physiology

 School of Basic Medical Sciences and Clinical Pharmacy

 China Pharmaceutical University

 24 Tongjiaxiang

 Nanjing, 210009

 86(25) 83271029


Rutgers, the State University of New Jersey, Piscataway, NJ

Department of Pharmaceutics, Ernest Mario School of Pharmacy

Ph. D. conferred June, 2005

Major: Pharmaceutical Sciences


(1) Studies on phytochemicals-mediated cellular signaling and chemoprevention against inflammation-associated carcinogenesis. (2) Nrf2- and Nlrp3-mediated signaling in regulating oxidative stress and inflammation.


  1. Liu XZhang XDing YZhou WTao LLu PWang YHu R*. Nuclear Factor E2-Related Factor-2 Negatively Regulates NLRP3 Inflammasome Activity by Inhibiting Reactive Oxygen Species-Induced NLRP3 Priming. Antioxid Redox Signal. 2016 Aug 9. [Epub ahead of print]

  2. Liu XZhou WZhang XLu PDu QTao LDing YWang YHu R*. Dimethyl fumarate ameliorates dextran sulfate sodium-induced murine experimental colitis by activating Nrf2 and suppressing NLRP3 inflammasome activation. BiochemPharmacol. 2016 Jul 15;112:37-49. doi: 10.1016/j.bcp.2016.05.002. Epub 2016 May 13.

  3. Du QWang YLiu CWang HFan HLi YWang JZhang XLu JJi H*, Hu R*. Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-β-catenin axis. Oncotarget. 2016 Feb 21. doi: 10.18632/oncotarget.7554.

  4.  Du Q, Wang Q, Fan H, Wang J, Liu X, Wang H, Wang Y*, Hu R*. Dietary cholesterol promotes AOM-induced colorectal cancer through activating the NLRP3 inflammasome. Biochem Pharmacol. 2016 Feb 24. pii: S0006-2952(16)00116-7. doi: 10.1016/j.bcp.2016.02.017.

  5.  Wang Y, Wang H, Qian C, Tang J, Zhou W, Liu X, You Q*, Hu R*. 3-(2-Oxo-2-phenylethylidene)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one (compound 1), a novel potent Nrf2/ARE inducer, protects against DSS-induced colitis via inhibiting NLRP3 inflammasome. Biochem Pharmacol. 2016 Feb 1;101:71-86.